Abstract
Objective:To observe the curative effects of four kinds of plant extracts nasal spray mixture (myrtle oil, hyaluronic acid, fucoidan, anthocyanin) on 161 patients with nasal mucosa dryness, hemorrhae and erosion. Methods:① Diagnosis: patients with nasal dryness, erosive and hemorrhae nasal septum mucosa confirmed by patients' complaints and nasal endoscopic test; ② Evaluation: the severity of subjective symptoms was evaluated by VAS score method from 0 to 10 points; the degree of mucosal lesions was divided into 0-8 points by nasal endoscopic test. ③ Intranasal Intranasal administration: 2 times per-day with 2 sprays on each side of the nasal cavity, and no less than 6-8 weeks. In the patients which with allergic rhinitis were also given conventional oral administration of montelukast at the same time. ④ Follow up and curative effect evaluation: VAS and nasal endoscopic test scores that before and after treatment was statistically processed; the patients' own how feels the treatment were evaluated; finally, doctor made the final evaluation based on the combined results of subjective and objective evaluation results before and after treatment, the patients' satisfaction with treatment effect. Results:① There were significant differences in VAS scores of 161 patients before and after treatment (P<0.01).② There were statistically significant differences in nasal endoscopic test scores of 104 patients before and after treatment (P<0.01). ③ Patients' satisfaction survey showed the satisfied with the compliance, tolerance and treatment effect was 95%. Conclusion:The mixed nasal spray of four plant extracts can effectively improve the dryness, hemorrhae and erosion of nasal mucosal.
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More From: Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology, head, and neck surgery
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