Abstract
A retrospective review of 5,000 patients studied over a period of three years showed that a second dose was necessary in 25% of gallbladder examinations; however, third and fourth doses gave no additional information. Nonopacification of the gallbladder after a second examination is diagnostic of disease when all extrinsic factors have been ruled out. Intravenous cholangiography may show calculi in a diseased gallbladder that was not opacified on the oral study, since it does not depend on the concentrating ability of the gallbladder for opacification; however, a radiographically normal gallbladder on intravenous cholangiography does not rule out nonobstructive cholecystitis or cholelithiasis.
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