Abstract

Myasthenia gravis(MG)is an autoimmune disease that the acetylcholine receptor antibody (AchR-Ab)mediated, complement dependent cell-mediated immunity involved in and against acetylcholine receptors in neuromuscular postsynaptic membrane. Recently, accumulating evidence convincingly emphasizes that autoantibodies play an important role in the pathogenesis of MG, such as AchR-Ab, Titin-Ab, RyR-Ab and MuSK-Ab. Different antibodies contained in MG patients’ serum may cause differences in patients' clinical features and pathogenesis of MG. The analysis of MG antibody levels before treatment can provide a more rational treatment, which also help us assess the effect of treatment. Key words: Myasthenia gravis; Autoantibodies; Titin antibody; Kv antibody; MuSK antibody

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