Abstract
ObjectiveTo explore the association between the neutrophil-to-lymphocyte ratio (NLR) and in-hospital heart failure (HF) in patients with ST-segment elevation myocardial infarction (STEMI) undergoing primary percutaneous coronary intervention (PCI). MethodsOur present study included 413 patients diagnosed with STEMI and treated with primary PCI. We performed logistic regression models to evaluate the relationship between the NLR and in-hospital HF risk in subjects diagnosed with STEMI. ResultsThe incidence of HF after STEMI increased significantly with increasing NLR tertiles (the incidences of the first, second, and third tertiles were 5.07 %, 13.04 %, and 23.36 %, respectively; P < 0.001). Multivariate logistic regression model showed that elevated NLRs significantly increased the risk of in-hospital HF after adjusting for multiple potential covariates. The risk of HF in the second and third NLR tertile groups was 1.27 times greater (95 % CI, 0.42–3.92) and 3.09 times greater (95 % CI, 1.06–9.02) than that in the first tertile group (P for trend = 0.04). Moreover, the in-hospital HF risk increased by 58 % with per 1-SD increment in the NLR (OR, 1.58; 95 % CI 1.24–2.03; P < 0.001). ConclusionsOur study demonstrated that the NLR is positively correlated with in-hospital HF risk and is an independent predictor for in-hospital HF in STEMI subjects.
Published Version
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