Abstract

The neuropsychological impact of the CoVID-19 pandemic on the mental wellbeing of individuals – what have we learnt thus far

Highlights

  • The novel Corona virus disease (COVID-19) originated in Wuhan, Hubei Province in China in November 2019

  • Once in the central nervous system (CNS), SARS CoV-2 interacts with Angiotensin Converting Enzyme-2 (ACE-2) receptors to traverse the capillary endothelium and instigate a cascade of haemorrhagic events [18]

  • It is known that this condition has been associated with cytokine storms [20], and such cytokine storms have recently been reported in severe cases of COVID-19 [21,22]

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Summary

Introduction

The novel Corona virus disease (COVID-19) originated in Wuhan, Hubei Province in China in November 2019. COVID-19 is the result of infection with the positive-sense single stranded Severe Acute Respiratory Distress Syndrome Corona Virus-2 (SARS CoV-2). It escalated drastically to become a global pandemic with more than 124.8 million people infected with SARS CoV-2 and yielding a death toll of more than 2.74 million by March 2021 [1]. COVID-19 has spread to affect over 213 countries with the greatest number of cases being reported in the United States. While governments globally have implemented immediate action to contain the spread of SARS CoV-2 and limit the number of people infected, there has been minimal plans to address the mental health and any psychological issues originating from a catastrophe of this magnitude. The need for prompt action and prioritisation of appropriate healthcare services for those with underlying psychological and psychiatric vulnerabilities have been clearly identified [3,4,5]

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