The Neurobiology of Stress Reactivity and Emotion Dysregulation in Children at Risk for Depression

Abstract

Event Abstract Back to Event The Neurobiology of Stress Reactivity and Emotion Dysregulation in Children at Risk for Depression Ian H. Gotlib1* 1 Stanford University, Department of Psychology, United States Clinically significant depression is among the most prevalent and costly of all psychiatric disorders. Major theories of depression have typically focused independently on interpersonal, cognitive, biological, or genetic aspects of this disorder. In this talk I will discuss findings from a project in which we are conducting an integrative examination of these factors, in the broader context of assessing emotion regulation and stress reactivity, as they affect vulnerability to depression. We are assessing and following a large sample of young girls who are at elevated risk for depression by virtue of having a family history of the disorder. We are examining information-processing biases, HPA-axis functioning, patterns of anomalous neural structure and activation, and genotype, and have obtained exciting initial data in which offspring of mothers with recurrent depression already resemble depressed adults despite not yet having experienced an episode of depression themselves. I will describe aspects of these data, focusing in particular on neural and genetic findings, in elucidating the nature of the associations among stress reactivity, emotion dysregulation, and risk for depression. These data should help to identify critical areas of dysfunction that may serve as targets for programs designed to prevent the onset of depression. Conference: Conference on Neurocognitive Development, Berkeley, CA, United States, 12 Jul - 14 Jul, 2009. Presentation Type: Oral Presentation Topic: Emotional and social behavior Citation: Gotlib IH (2009). The Neurobiology of Stress Reactivity and Emotion Dysregulation in Children at Risk for Depression. Conference Abstract: Conference on Neurocognitive Development. doi: 10.3389/conf.neuro.09.2009.10.028 Copyright: The abstracts in this collection have not been subject to any Frontiers peer review or checks, and are not endorsed by Frontiers. They are made available through the Frontiers publishing platform as a service to conference organizers and presenters. The copyright in the individual abstracts is owned by the author of each abstract or his/her employer unless otherwise stated. Each abstract, as well as the collection of abstracts, are published under a Creative Commons CC-BY 4.0 (attribution) licence (https://creativecommons.org/licenses/by/4.0/) and may thus be reproduced, translated, adapted and be the subject of derivative works provided the authors and Frontiers are attributed. For Frontiers’ terms and conditions please see https://www.frontiersin.org/legal/terms-and-conditions. Received: 06 Jul 2009; Published Online: 06 Jul 2009. * Correspondence: Ian H Gotlib, Stanford University, Department of Psychology, Stanford, CA, United States, ian.gotlib@stanford.edu Login Required This action requires you to be registered with Frontiers and logged in. To register or login click here. Abstract Info Abstract The Authors in Frontiers Ian H Gotlib Google Ian H Gotlib Google Scholar Ian H Gotlib PubMed Ian H Gotlib Related Article in Frontiers Google Scholar PubMed Abstract Close Back to top Javascript is disabled. Please enable Javascript in your browser settings in order to see all the content on this page.