Abstract
The need for registries in the early scientific evaluation of surgical innovations.
Highlights
Randomized controlled trials (RCTs) represent the gold standard for evaluation of the safety and efficacy of surgical interventions
In particular, by the reaction to the introduction of laparoscopic cholecystectomy, which was greeted by Sir Alfred Cushieri as the “greatest unaudited procedure in the history of surgery” (3)
Laparoscopic cholecystectomy had already become established in many hospitals worldwide
Summary
Randomized controlled trials (RCTs) represent the gold standard for evaluation of the safety and efficacy of surgical interventions. The first report on a prospective randomized trial comparing laparoscopic with open cholecystectomy were published in
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