The ‘muffin test’ – a potential alternative to formal oral glucose tolerance test (OGTT) for the detection of impaired glucose tolerance (IGT)

Abstract

OBJECTIVE: For better tolerability and reflecting more physiologic post-meal glucose excursions, a muffin containing glucose, lipid and protein may help identify women at risk of metabolic syndrome. We reported preliminary results from the KEEPS (Kronos Early Estrogen Prevention Study) showing the “Muffin Test” (MT) compared favorably to OGTT. Here we compare the effectiveness of the MT versus OGTT for diagnosing IGT in different patient populations.