Abstract
Background: The COVID-19 pandemic is significantly affecting the functioning of the entire healthcare system. The disease itself may be associated with thromboembolic complications. The purpose of this study is to compare patients with acute coronary syndrome (ACS) and patients with ACS who were diagnosed with COVID-19 in terms of their clinical profile, management, treatment complications, and prognosis. Methods: We analyzed 47,940 cases of patients treated for ACS in 2020, including 44,952 patients (93.8%) who were not diagnosed with COVID-19 and 2988 patients (6.2%) who tested positive for COVID-19. Results: Patients with COVID-19 were significantly more likely to experience out-of-hospital sudden cardiac arrest (7.9 vs. 1.1%; p < 0.0001) and be transported directly to a catheterization laboratory (21.3% vs. 8.1%; p < 0.0001). Mortality was significantly higher in this group (0.9% vs. 0.4%; p < 0.0001). The risk of perioperative death was increased by age over 65 years, use of glycoprotein IIb/IIIa inhibitors (GPI IIb/IIIa), femoral access, critical left main stem coronary artery (LMCA) vascular lesions, ST elevation myocardial infarction (STEMI), and no-reflow phenomenon. Conclusions: Despite the pandemic, patients with COVID-19 were treated equally to healthy patients. Efficient organization of the healthcare system allowed the prompt transportation of patients to catheterization laboratories. The study group was characterized by a worse prognosis that was affected by multiple factors.
Highlights
We aimed to identify the most significant factors that contributed to increased perioperative mortality in the catheterization laboratory
Clinical characteristics revealed that patients with COVID-19 were younger, with less frequent episodes of previous myocardial infarction, percutaneous coronary intervention (PCI) or coronary aortic bypass grafting (CABG), and arterial hypertension
In our analysis of 2988 COVID-19(+) patients, we found that more of them used direct transportation
Summary
The epidemic, a pandemic, spread around the whole world. 229,858,719 cases of the disease have been recorded worldwide (including 4,713,543 deaths). In Poland, as of September 2021, 2,901,674 cases have been recorded (including 75,551 deaths) [2]. Despite countermeasures coordinated on a large scale by the World Health Organization (WHO), there has been an unprecedented spread of the pandemic. The COVID-19 pandemic is significantly affecting the functioning of the entire healthcare system. ACS who were diagnosed with COVID-19 in terms of their clinical profile, management, treatment complications, and prognosis. Methods: We analyzed 47,940 cases of patients treated for ACS in 2020, including 44,952 patients (93.8%) who were not diagnosed with COVID-19 and 2988 patients (6.2%). The risk of perioperative death was increased by age over
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