The metabolism of neutral lipids in the spur dogfish, Squalus acanthias.

Abstract

AbstractCell free studies have shown that liver and intestine are the major sites of synthesis of triacyl glycerols inSqualus acanthias. The liver and to a lesser extent the intestine and stomach are major sites of wax ester synthesis. Muscle does not synthesize either triacyl glycerols or wax esters significantly. In vivo studies have shown that intravenously injected (3H) fatty alcohol is massively oxidized to (3H) fatty acid, the bulk of which appears in muscle. Liver appears to export both free fatty acids and triacyl glycerols to serum and thence to muscle. Free fatty acids, triacyl glycerols, wax esters and cholesteryl esters are all turned over within 48 hr inSqualus serum. The turnover of triacyl glycerols greatly exceeds the turnover of alkyl diacyl glycerols.