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Abstract
A year ago it was observed that an intravenous injection of a small amount (0.2 c.c.) of immune serum causes the disappearance, within ten minutes'time, of the bacteria from the blood of a rabbit having a pneumococcic septicaemia. It was decided to investigate the above phenomenon in the hope of ascertaining, if possible, the manner of action of anti-pneumococcic serum.In the light of our results concerning the behavior of typhoid bacilli in the circulation of normal rabbits, we believed it possible that whole rabbit blood plus immune serum killed the pneumococci. Therefore rabbit blood was taken in hirudin; varying amounts of immune serum were added to the hirudin blood; definite quantities of bacteria were added and plates made immediately after starting the experiments, and at intervals for twenty-four hours. The colonies were found much reduced in the tubes containing the immune serum and whole blood, but after twenty-four hours all tubes were “saturated” with bacteria. It was believed that the immune ...
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