Abstract
A method to estimate plutonium content from a limited number of samples of lungs and pulmonary lymph nodes obtained at autopsies of former Mayak Production Association (MPA) workers is described. Historically from one to five samples of lung lobes and one to three respiratory lymph nodes (bronchopulmonary, tracheobronchial and paratracheal) were collected. The samples were used to estimate organ plutonium contents for cases where incomplete sets of samples were obtained, i.e. one to four lung lobes and one to two lymph nodes. This method was developed and validated using individual measurement data from 259 MPA autopsy cases with complete lung samples (five lobes) and three lymph nodes. A good correlation of plutonium content in measurements of two and four lung samples with the content estimate by five lung samples was obtained. The correlations with the individual lymph nodes were less robust than with the lung. The data are used to develop biokinetic, dosimetry and risk models for humans exposed to plutonium.
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