Abstract
Missed opportunities for vaccination (MOV) may be among the factors responsible for suboptimal vaccination coverage in South Africa. However, the magnitude and determinants of MOV in the country are not known. Thus, this study seeks to assess the prevalence and determinants of MOV in the country. South Africa is sub-divided into nine administrative provinces. We used nationally representative data from the 2016 South African Demographic and Health Survey. We considered MOV to have occurred if a child aged 12–23 months old had not taken all scheduled basic vaccine doses despite having any of the following contacts with health services: delivery in a health facility; postnatal clinic visit; receipt of vitamin A; and any child-related treatment at a health facility. Multilevel logistic regression was used to determine factors associated with MOV. The national prevalence of MOV among children aged 12–23 months was 40.1%. Children whose mothers attended facility-based antenatal care were considerably less likely to experience MOV than those whose mothers did not attend antenatal care: odds ratio (OR) 0.41, 95% confidence interval (CI) 0.19 to 0.88. Conversely, the independent predictor of an increased MOV among children was residence in either the Gauteng province (OR 2.97, 95% CI 1.29 to 6.81) or Mpumalanga province (OR 2.32, 95%CI 1.04 to 5.18); compared to residence in the Free State province. Our findings suggest a high burden of MOV among children in South Africa and that MOV may be associated with individual and contextual factors. The findings also underscore the need for further exploration of the contextual factors contributing to MOV in South Africa.
Highlights
Vaccines currently save more than three million lives from vaccine-preventable diseases every year worldwide [1]
Our findings suggest a high burden of Missed opportunities for vaccination (MOV) among children in South Africa and that MOV may be associated with individual and contextual factors
In low- and middle-income countries (LMICs), the benefits of vaccines are not being maximised for children as routine immunisation coverage remains suboptimal [2]
Summary
Vaccines currently save more than three million lives from vaccine-preventable diseases every year worldwide [1]. Vaccines can only prevent diseases if they reach the intended target populations [2]. In low- and middle-income countries (LMICs), the benefits of vaccines are not being maximised for children as routine immunisation coverage remains suboptimal [2]. LMICs, South Africa is experiencing challenges with optimising its national immunisation coverage, with a gradual decline in uptake of the third dose of diphtheria–tetanus–pertussis-containing vaccines (DTP3) from 85% in 2014 to 77% in 2019 [3]. Missed opportunities for vaccination (MOV) are said to be among the factors responsible for the suboptimal coverage [4]. MOV refer to any contact with health services by an individual who is eligible
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