Abstract

The Long-Term Impact of Excision of Benign Non-Endometriotic Ovarian Cysts on Ovarian Reserve and Reproductive Performance: A Cohort Study Long-Term Ovarian Reserve Status After Ovarian Cystectomy

Highlights

  • Ovarian cystectomy is a very common procedure in gynaecological practice

  • To the best of our knowledge, this is the first study on the long-term impact of ovarian cystectomy on ovarian reserve and reproductive performance

  • We found no statistically significant difference in circulating Anti Müllerian Hormone (AMH) and all other ovarian reserve markers between both groups

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Summary

Introduction

Ovarian cystectomy is a very common procedure in gynaecological practice. There has recently been a growing concern that this procedure is associated with a significant compromise to ovarian reserve. Previous research reported that cystectomy was associated with concomitant excision of normal ovarian tissue resulting in significant follicle loss [1,2]. Several recent studies have consistently reported decline in ovarian reserve as measured by circulating Anti Müllerian Hormone (AMH) after excision of benign ovarian cysts [3,4,5,6,7,8,9]. Our recent meta-analysis has shown about 38% decline in circulating AMH after excision of benign non-endometriotic ovarian cysts, which was sustained for up to six months [10].

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