Abstract
Countercurrent chromatography is a liquid-liquid partition chromatography method allowing high-resolution purifications. It utilises the hydrodynamic behaviour of two immiscible liquid phases in coil columns undergoing a planetary motion generated by a synchronous coil planet centrifuge. In this study planetary rotation is applied to liquid-liquid flows in two types of ring geometries. The influence of the epicyclic force field is studied by applying a variety of different operating conditions, namely rotational speed and the ratio of the planet and sun radii known as the beta value. The results show that variation of the beta value has far greater influence on phase distribution than variation of the rotational speed.
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