Abstract

Acquired aplastic anemia is a refractory blood disease for children, and severe acquired aplastic anemia can be a great threaten for life.China is a high incidengce area, children at a period during which this disease can mostly occur.In China, except some congenital aplastic anemia, most children who have this diease is acquired aplastic anemia.In 2009, the Britain society of hematology recommended Guidelines for the diagnosis and management of aplastic anaemia, which represented the latest diagnosis and treatment principle and mainstream view of the clinical methodology about aplastic anemia.They make it clear that the main treatment for the disease are allogeneic hemato-poietic stem cell transplantation(allo-HSCT) and immunosuppressive therapy(IST). This article collects the documents in recent 5 years, and provides a overview about the latest advance of the allo-HSCT and IST in the word. Key words: Acquired aplastic anemia; Allogeneic hematopoietic stem cell transplantation; Immunosuppressive therapy; Effectiveness

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