The laboratory diagnosis of viral hepatitis in the era of antiviral therapy

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In recent years, great achievements have been made in the therapy of viral hepatitis B and viral hepatitis C, as majority of hepatitis C patients can be clinically cured. Though current antiviral therapy is still unable to eradicate hepatitis B virus in infected hepatocyte and few patients could achieve HBsAg loss or seroconversion, end–stage liver disease like cirrhosis, liver failure and hepatocellular carcinoma have been dramatically prevented. The advances in treatments have prompted the progress in laboratory diagnosis of viral hepatitis. Here we review the progress in the field. (Chin J Lab Med, 2015, 38: 148–150) Key words: Hepatitis, viral, human; Clinical laboratory techniques; Hepatitis B surface antigens; Hepatitis B e antigens; Hepatitis C antibodies