Abstract
SIGNIFICANCE OF IMPURITY IN TECHNICAL INDUSTRIAL PRODUCTS While the effect of added or remaining impurity is to decrease the toxicity of technical formulations when the impurity is of lower toxicity, the work of the author and co-workers! on aldrin and dieldrin and of Ingles'' on chlordane, for example, demonstrated that the presence of process by-products in technical preparations of these insecticides greatly increased their toxicity. Subsequent investigation showed these impurities to be many times as toxic as the pure compound. The synergistic action of certain non-toxic additives must be considered, e.g., piperonyl butoxide on pyrethrin. In America, technical products are tested even when the toxicity of the principal active ingredient is known.
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