Abstract

Membrane curvature is known to play an important role in cell growth, division and movement. Different lipid and membrane proteins can influence the cell's shape by changing the membrane curvature. Developing new technologies is vital for investigating and understanding the processes involved when membranes deform. We present an approach to study membrane curvature in giant unilamellar vesicles (GUVs) using microfluidic technology. Micron-sized channel networks in microfluidic devices are ideally suited for the manipulation and imaging of biological structures.

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