Abstract

Prunioside A is a unique, highly oxidized monoterpene glycoside isolated from the methanol extract of Spiraea prunifolia var. Simpliciflora's root. The ester derivatives were synthesized from the hydrolyzed compounds of prunioside A by <TEX>${\beta}$</TEX>-glucosidase. The derivatives showed suppressive effects on the generation of nitric oxide in murine machrophage-like RAW 264.7 cells stimulated by lipopolysaccharide and interferon- <TEX>${\gamma}$</TEX>.

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