The Influence of Using a Static Diastolic Geometry in ECG Imaging

Abstract

One of the common choices when performing electrocardiographic imaging (ECGI) is that the cardiac geometry is in a static, diastolic state. To test the influence of this approximation, we compared epicardial potential maps and isochrones during systolic and diastolic geometries in four patients. Zero-th order Tikhonov regularization was used to reconstruct ventricular epicardial potentials. A spatiotemporal estimation method was then used to determine the activation and recovery times from the reconstructed epicardial electrograms. Activation times (AT), recovery times (RT) and electrogram correlation coefficients (CC) were compared for both geometries. Furthermore, CC and differences in AT/ RT were correlated against the linear movement and a substitute for rotational movement. Poor correlation was found between linear/rotational movement and reconstruction differences. Overall, agreement between epicardial potential maps and isochrones of both geometries was high when assessed quantitatively, but regional differences might occur for qualitative interpretation. These differences mostly occurred in areas of flat T-waves. This novel, more accurate quantification of the influence of assuming a diastolic geometry in ECGI may further help in interpreting ECGI measurements.