The influence of the countermeasures targeted at adverse reaction of chemotherapy on the quality of life of the patients with metastatic breast cancer

Abstract

Objective To study the influence of the countermeasures targeted at adverse reaction of chemotherapy on the quality of life of the patients with metastatic breast cancer. Methods A total of 96 cases of patients with recurrent and metastatic breast cancer treated in our hospital from January to July 2015 were selected as the study objects.They were randomly divided into observation group and control group, 48 cases of each group.Patients in the observation group were given symptomatic nursing targeted at adverse reaction of chemotherapy, while patients in the control group were given conventional nursing.The quality of life (including body condition, character, cognition, society and general health condition ), the occurrence rate of anxiety symptom and adverse reaction of the two groups 3 months after nursing were compared. Results Three months after nursing, the general health condition scores of the observation group were (80.52±23.12)scores which were obviously higher than that of the control group(71.43±18.43)scores (P<0.05). The anxiety symptom rate and adverse reaction occurrence rate of the observation group were 16.7% and 12.5% respectively, which were obviously lower than the control group's 39.6% and 31.3%(P<0.05). Conclusion Symptomatic nursing targeted at adverse reaction of chemotherapy can reduce the toxic and side effect, relieve the anxiety and improve the patients' quality of life.Thus, it deserves to be applied and promoted in the clinical field. Key words: Recurrent and metastatic breast cancer; Chemotherapy; Adverse reaction; Symptomatic nursing