Abstract
The rotary processor can be used for single step spheroid production directly from powder with multiple formulation and process variables involved. In this study, a frictional base plate with teardrop studs was used. Four selected independent variables, base plate rotational speed during liquid addition (A), spray rate of water (B), total amount of water added (C) and base plate rotational speed during the tumbling stage (D), were put into an orthogonal design with three levels for each variable. Mean spheroid size and size distribution were used as the response variables to evaluate the effect of these independent variables. The variables C and D were identified as more important among the four variables and should be at optimal levels for producing good quality spheroids.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
