Abstract
To explore the impact of Nutren on postoperative nutritional status, incision healing and inflammation in patients with colon cancer (CC). Division of 94 patients with CC as the research object was into the observation group (51 cases) and the control (43 cases) on the grounds of postoperative enteral nutrition support (ENS). Analysis of the influence of Nutren on postoperative nutritional status, inflammation and incision healing was performed. No distinct differences between the two groups in surgical efficacy, survival rate, distant metastasis rate and recurrence rate after surgery of 2 years (P > 0.05); The incision healing time of the observation was shorter versus the control, and the incision healing was superior versus the control. Hemoglobin, albumin and total plasma protein of 14 d after operation were elevated versus the control, and c-reactive protein (CRP), tumor necrosis factor-α (TNF-α), and interleukin (IL)-6 were declined versus the control (P < 0.05). Giving of enteral nutrition support is to patients after CC radical resection, which is available to ameliorate the nutritional status, accelerate incision healing, and decline inflammation.
Highlights
Colon cancer (CC) is a malignant tumor emanating from the colonic mucosa epithelium
We found that Nutren was available to mitigate and ameliorate the patient’s statusthe inflammatory of CC patients after surgery, which may provided a new nutritional support method to alleviate the phenomenon of poor nutrition and prevent intestinal barrier function damage in the body to a certain extent
The incidence of postoperative complications in the observation is distinctively elevated versus the control, manifesting that postoperative enteral nutrition therapy (ENT) with Nutren is able to decline the incidence of complications
Summary
Colon cancer (CC) is a malignant tumor emanating from the colonic mucosa epithelium. Patients frequently present with symptoms like hematochezia and abdominal pain. Laparoscopic radical resection of CC, the crucial method for the treatment of CC, is available to remove the lesion and mitigate the impact of the lesion on the body. This invasive treatment method inevitably leads to damage to the body and influence the integrity of intestinal mucosa (Bakker et al, 2020). An enteral nutrition powder, primarily composed of indispensable amino acids involving Gln and arginine, as well as other nutrients like vitamins and minerals, which is prevalently adopted in postoperative ENS for multiple diseases, but its application value in ENT of CC after surgery was continuously in the exploratory stage. This study was to explore the influence of Nutren on postoperative nutritional status, inflammation and incision healing in CC patients, and references for the formulation of postoperative treatment methods for patients was offered
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