Abstract
The magnesium deficiency syndrome in white rats can be aggravated by the addition of high levels of pyridoxine hydrochloride to the diet. In these studies, the mortality rate of magnesium deficient rats varied in direct proportion to the dietary concentration of pyridoxine hydrochloride. This effect was not produced by increasing the thiamine hydrochloride content of the diet. The present studies did not demonstrate a consistent difference in serum magnesium concentration between the magnesium deficient rats receiving a normal pyridoxine supplement and those receiving a high pyridoxine supplement.
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