Abstract
BackgroundAir pollution has been associated with adverse cardiovascular effects. ObjectiveTo measure the association between air pollution, spirometry, blood pressure, and exercise capacity. MethodsWe used data from 5604 subjects collected during the Canada Health Measures Survey to test the association between air pollution measured on the day of the survey and spirometry (n=5011 subjects), blood pressure, and exercise capacity (n=3789 subjects). ResultsAn interquartile range (IQR) increase in ozone (17.0ppb) was significantly associated with a 0.883% higher resting heart rate, a 0.718% higher systolic and 0.407% higher diastolic blood pressure, a 0.393% lower FEV1/FVC expressed as a percentage of predicted, and a 1.52% reduction in the aerobic fitness score (p<0.05). Resting systolic and diastolic blood pressure were approximately 0.5mmHg higher for an (IQR 4.5μg/m3) increase in PM2.5 (IQR 4.5μg/m3) and 1mmHg higher for a 12.6ppb increase in NO2 (IQR 12.6ppb). An increase in PM2.5 was also associated with an approximate 0.4% decrease in percent predicted FEV1 and FVC (p<0.05). ConclusionExposure to higher concentrations of air pollution was associated with higher resting blood pressure and lower ventilatory function. Ozone was associated with reduced exercise capacity.
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