Abstract
Indices of carbohydrate metabolism and histological structure endocrine tissue of the pancreas in rabbits with experimental diabetes after intrasplenic allo- and xenotransplantation of pancreatic islets of neonatal animals has been studied. It was found that intrasplenic transplantation of islets restores and maintains the long-term within the physiological norm of carbohydrate metabolism without hypoglycemic episodes. Intrasplenic transplantation pancreatic islets activates of the autoregeneration in endocrine pancreatic tissue of recipient animals, leading to the pool restoration of insulin-producing β-cells.
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