Abstract
Perinatal infections remain a significant cause of neonatal morbidity and mortality. Mother-to-child transmission (MTCT) can occur in utero (rubella, CMV, syphilis, Toxoplasma), intrapartum (HBV, HIV, group B streptococci, enteric gram-negative organisms, gonococci, chlamydiae) or during post-natal period (TBC, HIV, CMV) The microorganism type and the timing of infection influence the outcome that includes spontaneous abortion, intrauterine growth restriction, premature birth, stillbirth, congenital malformation and symptomatic or asymptomatic neonatal infection.
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