Abstract
Virus crystals can incorporate a wide range of unusual impurities, not possible for conventional crystals, or even most protein crystals because of the large size of their constituent particles. These impurities include anomalous virions, satellite viruses and biological fibers. Examples of several of these unusual impurities are presented here, along with some of the consequences for the crystal lattices. The high solvent content, the forgiving character of the lattice and the plasticity of the virions allow these incorporations to be possible.
Highlights
Previous studies using atomic force microscopy have shown that protein crystals incorporate a wide variety of impurities, which frequently produce defects in the lattice
We have further examined a variety of virus crystals using atomic force microscopy and present here some of the unique kinds of impurities that are incorporated into these crystals
Macromolecular crystals permit the incorporation of a wide variety of impurities having sizes comparable to, or even much larger than the asymmetric units comprising the crystals
Summary
Previous studies using atomic force microscopy have shown that protein crystals incorporate a wide variety of impurities, which frequently produce defects in the lattice. We have further examined a variety of virus crystals using atomic force microscopy and present here some of the unique kinds of impurities that are incorporated into these crystals.
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Schedule a callMore From: Acta Crystallographica Section D Biological Crystallography
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