Abstract
Objective. To evaluate the incidence and causes of atrial fi brillation in hospitalized patients of therapeutic profi le and to compare the dynamics of these parameters over past 25 years.Design and methods.We analyzed 14595 medical histories of the faculty therapy clinic of Pavlov St Petersburg State Medical University for the periods from 1985 to 1990 years and from 2005 to 2010 years.Results.The incidence of atrial fi brillation increased by 1,7 times over the past 25 years. There is a signifi cant increase in the number of patients with atrial fi brillation in combination with co-morbidities: obesity — 1,9 times, essential hypertension — 1,8 times, and type 2 diabetes mellitus — 3-fold increase. The incidence of valvular heart diseases in patients with atrial fi brillation decreased by 1,9 times from 1985 to 2010 year. Statistical signifi cance of differences was assessed by Fisher’s exact test (p < 0,0001).Conclusion.The number of hospitalized patients with atrial fi brillation signifi cantly increased over the past 25 years. The number of patients with nonvalvular atrial fi brillation signifi cantly increased from 1985 to 2010 year and the number of patients with rheumatic valvular heart disease with atrial fi brillation decreased.
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