Abstract

Vitamin D is involved in numerous reactions in the human body, as well as in the regulation of about 3% of the human genome. Research shows that insufficient concentration of vitamin D in the blood is found in 40-50% of the population. The total intake of vitamin D through food is very low, only 20% of the total daily needs. This paper shows importance of vitamin D supplementation in different periods of woman's life. To estimate average plasma levels of vitamin D3 in all researched group and establish which group should be supplemented with vitamin D3. The study included 182 women, divided in appropriate groups according to age, who came regularly for annual gynecological check-ups. Total concentration of 25 (OH) vitamin D in plasma was determined by a competitive immunochemical test. The average value of vitamin D3 plasma level in patients aged 18 to 45 was 24,409 ng/ml, in the patients aged 46 to 55 years was 27,519 ng/ml and in the patients aged 56 and over 31,960 ng/ml. The results obtained indicate a vitamin D shortage in the first two groups of patients and an adequate vitamin D3 levels in third group of patients. Vitamin D supplementation is required in patients aged 18 to 55 years. Vitamin D shortage is present in two groups of patients. Because of complex role that this vitamin plays in numerous reactions in human body adequate supplementation is necessary.

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