Abstract
The aim of the research was to study the effect of the drug glimepiride on adipose tissue hormones levels (leptin, resistin) and cytokines (IL-2, IL-6, TNF-α) in type 2 diabetes. 28 patients with newly diagnosed type 2 diabetes were examined before and after 12 months of hypoglycemic glimepiride monotherapy. The results indicate that the normalization of carbohydrate metabolism, cytokines levels after the treatment is caused not only by the direct influence of glimepiride in β-cells of the pancreas, but also by its ability to modulate the secretion of proinflammatory cytokines.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
