Abstract
Background: An ablation targeting ganglionated plexi (GP) with pulmonary vein isolation (PVI) and/or left atrium (LA) modification has been reported to have the potential to improve an outcome after ablation of atrial fibrillation (AF). However, it is not clear whether PVI per se affects the GP. Methods and Results: We identified the sites of LA showing a high grade atrioventricular (AV) block by an application of high frequency stimuli (HFS) as the location of GPs (superior left GP [SLGP], anterior right GP [ARGP], Marshall tract GP [MTGP], inferior right GP, inferior left GP) in a 75 year-old-woman presenting with drug refractory persistent AF. After successful PVI using a generally accepted approach with CARTO system, the high grade AV block induced by the HFS that had been observed before the PVI was in turn not identified at the location of SLGP, ARGP and MTGP. Conclusions: PVI possibly provides GP modification as one of the therapeutic effects for AF.
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