Abstract
Morbidity and mortality after lower limb amputation (LLA) remain disappointingly high. This study aimed to assess the impact of previous ipsilateral vascular intervention on outcomes after major LLA. Prospective data were collected for all major LLAs performed between January 2010 and December 2011. Those who underwent a primary amputation were compared with secondary amputees to establish if previous interventions were a risk factor for morbidity and mortality. One hundred forty-eight patients underwent LLA during the study period; 102 were primary amputees, and 46 (31.1%) had undergone previous ipsilateral revascularization. The groups were well matched for demographics and comorbidities. Those who underwent secondary amputations were older (P=0.016) and more likely to suffer from hypercholesterolemia (P<0.001). Patients who had undergone a previous intervention were more likely to need revision surgery (17% vs. 4.5% P=0.027). Previous intervention was not found to be a risk factor for more proximal amputation level (P=0.341) or increased postoperative mortality (P=0.782), however. Patients who have undergone previous revascularization may be at higher risk of revision surgery. Survival after major LLA does not appear to be associated with previous revascularization attempts.
Published Version
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