Abstract
Advancing maternal age, especially after the age of 35, is associated with a continual decline in fertility potential. Recently, sophisticated techniques have been refined that make cryopreservation (freezing) of oocytes (eggs) a safe and efficacious method of pursuing fertility preservation in relatively young women. This technology has the potential to make a significant social impact by empowering women to have greater control over their reproductive future
Highlights
Advancing maternal age, especially after the age of 35, is associated with a continual decline in fertility potential
Many centers around the world have repeatedly demonstrated competence in oocyte cryopreservation with resulting pregnancies [1,2]. This success led to the 2012 decision by the American Society for Reproductive Medicine (ASRM) to remove the experimental label from oocyte cryopreservation [1]
While pregnancy rates associate with embryo cryopreservation were encouraging, survival rates of cryopreserved oocytes was exceptionally poor [5]
Summary
Especially after the age of 35, is associated with a continual decline in fertility potential. The technology used to freeze (cryopreserve) human eggs (oocytes) in the context of an In Vitro Fertilization (IVF) cycle has significantly advanced [1,2,3]. Many centers around the world have repeatedly demonstrated competence in oocyte cryopreservation with resulting pregnancies [1,2].
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