Abstract
INTRODUCTION: Seventy-six samples were collected from sixteen canine blood donors at every blood donation performed in accord with the canine donor selection guidelines. Statistical analysis of ELISA OD values revealed no significant variation of anti-rabies antibodies values during repeat donations. Our results support the statement that blood donation does not affect the immune status of donors.
 OBJECTIVES: The study aimed to assess the immune status against rabies among the canine blood donors in a Romanian canine blood bank
 METHODS: Serum samples (n=76) were collected from pet owned dogs (n=16) recorded in the blood bank register of a Romanian blood bank were performed with the immunological status of the investigated canine blood donors was evaluated using the indirect ELISA commercial kit PLATELIA RABIES II (BIO-RAD, France) as per the manufacturer's instructions
 RESULTS: The overall picture of ELISA OD results revealed non-significant variation between and within D1-D6 groups of values (p>0.05, F<Fcrit).
 CONCLUSION: The next studies topic would be to compare the results provided by the ELISA technology with FAVN.
Highlights
Seventy-six samples were collected from sixteen canine blood donors at every blood donation performed in accord with the canine donor selection guidelines
The transfusion technology initially developed for human health became more available for companion animals, which led to the design and set up of veterinary blood banks Radulescu et al (2009)
Like in human transfusion medicine, the canine blood bank use pretransfusion testing for canine erythrocyte antigens Yagi and Bean (2016); Ionescu et al (2018a) and blood-borne pathogens Reine (2004); Ionescu et al (2018b) to minimize the risks associated with blood transfusion
Summary
Seventy-six samples were collected from sixteen canine blood donors at every blood donation performed in accord with the canine donor selection guidelines. Like in human transfusion medicine, the canine blood bank use pretransfusion testing for canine erythrocyte antigens Yagi and Bean (2016); Ionescu et al (2018a) and blood-borne pathogens Reine (2004); Ionescu et al (2018b) to minimize the risks associated with blood transfusion In this regard, our previous studies established that canine blood donors of Romania blood banks were 56.19% (59/105) DEA1 positive [37.29% (22/59) male, and 88.13% (52/59) purebred] and 43.81% (46/105) DEA1 negative [56.52% (26/46) male, and 93.48% (43/46) purebred] Ionescu et al (2018a), provided negative results for B. burgdorferi and E.canis/E. ewingii (0/1253), while 0.87% (11/1253) were positive for A. phagocytophilum/A. platys and 6.94% (87/1253) positive for D. immitis Ionescu et al (2018b). Vaccinating dogs against rabies aims to establish pre-exposure immunity and protect animals from contracting rabies and stop the further spread to humans or other animals (Cox et al (1977)
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