Abstract
Introduction: Palatine tonsils are paired masses of lymphoid tissue, which act as an immunologicbarrier against the entry of pathogenic agents into the respiratory and digestive tracts. Tonsillitis is acommon disease, especially among children. Chronic tonsillitis is a disease with repeated attacks ofacute tonsillitis or a sub-clinic form of a resistant or poorly treated infection. Aim: To determine theclinicopathological findings in various lesions of tonsillectomy in the palatine tonsil. Materials andmethods: This is a retrospective study where 105 (Unilateral-20, Bilateral) cases ofhistopathologically identified tonsillectomy specimens as well as 4 tonsillar biopsies were included.The available data for all the patients as regards age, sex, and clinical symptoms were collected.Sections were taken from tonsillectomy specimens from representative areas while tonsillar biopsieswere processed completely. Routine hematoxylin and eosin staining was done along with this specialstain- PAS (periodic acid- Schiff) for actinomycosis and ZN stain for AFB. Results: Amongst thecases, 78 cases showed chronic tonsillitis. 11 cases were chronic tonsillitis with actinomycosis, acutechronic tonsillitis in 07 cases, granulomatous tonsillitis in 03 cases, acute ulcerative tonsillitis withmicroabscesses in 01 case, and reactive lymphoid hyperplasia in 02 cases. Three malignancies wereobserved – Two cases of squamous cell carcinoma and one case of undifferentiatedcarcinoma/lymphoma. Conclusion: Chronic tonsillitis is a common problem facing in all age groups,Histopathology plays a significant role in diagnosing both benign and malignant lesions of the tonsil.
Highlights
Palatine tonsils are paired masses of lymphoid tissue, which act as an immunologic barrier against the entry of pathogenic agents into the respiratory and digestive tracts
Chronic tonsillitis is a common problem facing in all age groups, Histopathology plays a significant role in diagnosing both benign and malignant lesions of the tonsil
The current study report 105 cases of enlarged tonsils, out of which 101 were undergone for tonsillectomy
Summary
Palatine tonsils are paired masses of lymphoid tissue, which act as an immunologic barrier against the entry of pathogenic agents into the respiratory and digestive tracts. Conclusion: Chronic tonsillitis is a common problem facing in all age groups, Histopathology plays a significant role in diagnosing both benign and malignant lesions of the tonsil. The palatine tonsils are paired nodular masses of lymphoid tissue situated on either side of the oropharynx having an extremely remarkable role in the antimicrobial defense of the body [2]. They are covered by non-keratinized stratified squamous epithelium along with deep crypts that invaginate into the parenchyma, in which B– lymphocytes are found [3]. Various organisms including viruses like Reovirus, Adenovirus, Influenza virus, and Echovirus, and bacteria like beta-hemolytic Streptococcus are implicated in the causation of tonsillitis. One of the definite indications is asymmetric tonsil for histopathological evaluation to rule out malignancy [6,7]
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