The heat distribution of radiofrequency ablation in the ex vivo vertebral tumor model

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Objective To investigate the heat distribution of radiofrequency ablation (RFA) in the ex vivo vertebral tumor model and heat isolation effect of posterior cortical bone using UniblateTM Rita electrode,and to evaluate the valid range of RFA treating vertebral tumor lesion and the thermal protection of posterior cortical bone to the spinal cord.Methods Ten fresh lumbars excised from adult swines were used to creat the ex vivo vertebral tumor model.Radiofrenquency was performed at 75,80,85,90,and 95 ℃ with 1.0 cm and 2.0 cm electrode tips.The valid range of RFA was measured in the ex vivo vertebral tumor model with diffierent electrode tips and diffierent setting temperatures.Twenty fresh lumbars excised from adult swines were divided into intact posterior cortical bone group and defect posterior cortical bone group randomly,creating the intact posterior cortical bone tumor model and defect posterior cortical bone tumor model respectively.Radiofrenquency was performed at 95 ℃ with 2.0 cm electrode tip.The anterior and posterior temperature of posterior cortical bone in the ex vivo vertebral tumor model was recorded.Results RFA range in the ex vivo vertebral tumor modle didn' t exceed 5 mm at 75,80,85,90,and 95 ℃ with 1.0 cm electrode tip.The radiuses of RFA range in the ex vivo vertebral tumor model were (6.40 ±0.52),(7.40±0.71),(8.00 ±0.67),(8.20 ±0.63) and (8.30 ±0.68) mm at 75,80,85,90,and 95 ℃ with 2.0 cm electrode tip,respectively.The anterior and posterior temperature of posterior cortical bone in the intact group was (50.28 ±4.21) and (38.26 ±4.47) ℃ (P ＜0.05) ; The anterior and posterior temperature of posterior cortical bone in the defect group was (51.07 ± 4.23) and (49.27 ± 3.84) ℃ (P ＞ 0.05).Conclusion In the ex vivo vertebral tumor model,RFA was safe and effective with 2-cm electrode tip.Posterior cortical bone can protect the spinal cord in the process of RFA. Key words: Radiofrequency ablation; Vertebral tumor; Heat distribution