Abstract

The guiding principles for populational COVID-19 vaccine selection: A normative analysis through comparison of the strategies in Hong Kong and Singapore.

Highlights

  • Preliminary study showed similar efficacy to neutralise mutant Data not available [16] viruses that emerged from the UK and South Africa [15]

  • Summary on efficacies: Comirnaty proves to be superior to CoronaVac in terms of efficacy overall, for severe disease, for elderly people and for people at risk with comorbidities or obesity, and possibly against mutant viruses from the UK and South Africa

  • This is a sign that the immune response is successfully induced and the majority of these events were mild or moderate in severity, lasting only one day [17]. These self-limiting short term systemic reactions pose no significant health threat to the recipients. With this in mind as well as the better efficacy-safety profiles of mRNA vaccines, population-wide provision of mRNA vaccines instead of traditional ones are in full conformity with the ethical principles of beneficence and non-maleficence

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Summary

Tak Kwong Chan

COVID-19 vaccination campaigns are under way in many parts of the world to protect individuals, reduce overall infection and restore normality. My article aims to normatively derive the guiding principles for populational vaccine selection using comparison of the strategies in Hong Kong and Singapore. I briefly describe the vaccination campaigns in both cities and normatively derive the guiding principles for vaccine selection by an inquisitive and comparative approach Both cities acknowledge that the vaccination campaigns aim at protecting individuals against infection, safeguarding public health and restoring normality. The analysis compares the vaccine selection strategies in Hong Kong and Singapore and inquisitively questions which strategy better serves social interest of reducing overall infection and restoring normality, which strategy better serves the individual medical interests of the vaccine recipients and whether the efficacy-safety profiles of different approved vaccines should be compared. The guiding principles for populational vaccine selection are delineated

DIFFERENT VACCINE SELECTION STRATEGIES
EFFICACIES OF VACCINES
REDUCING INFECTION AND RESTORING NORMALITY
CONSIDERING INDIVIDUAL MEDICAL INTERESTS
Against mutant viruses
Should we compare different vaccines?
Deriving the guiding principles for vaccine selection
Relative risk
Findings
CONCLUSIONS
Full Text
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