Abstract

The three main approaches to studying the genetics of alcoholism have been twin studies, adoption and half-sibling studies, and genetic marker studies. Twin studies have demonstrated differences between monozygotic and dizygotic twin pairs in regard to alcohol use and abuse, but tend to be contradictory with regard to alcoholism. However, most adoption studies have confirmed the author's evidence that alcoholism runs in families, or is “familial.” While this is not synonymous with “hereditary” it may provide certain clues for future research. Genetic marker studies can help afford support for a biological factor in the etiology of alcoholism. Studies such as the one on sex-linked color-blindness in alcoholics should be replicated. Confirming data might indicate that at least certain types of alcoholism are associated with a genetic factor.

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