THE FORMOL-GEL REACTION IN BLOOD OF PATIENTS WITH CHRONIC RHEUMATOID DISEASES

Abstract

Article1 December 1940THE FORMOL-GEL REACTION IN BLOOD OF PATIENTS WITH CHRONIC RHEUMATOID DISEASESC. WESLER SCULL, PH.D., RALPH PEMBERTON, M.D., F.A.C.P.C. WESLER SCULL, PH.D.Search for more papers by this author, RALPH PEMBERTON, M.D., F.A.C.P.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-14-6-993 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptINTRODUCTIONStudies conducted in this laboratory on the protein fractions in the sera of arthritics clearly show that moderate and sometimes marked hyperglobulinemia is a significant feature among certain classes of arthritic subjects.6Associated with the increase in serum globulin there is an elevation in the fibrinogen of the corresponding plasma. These results are in substantial agreement with observations made by Aldred-Brown and Monroe1and by Davis.3Recognition of the presence of these features in a given case is of practical importance, inasmuch as an elevation in the level of the globulin or fibrinogen in the blood shows the presence...Bibliography1. ALDRED-BROWNMONROE GRJM: The plasma protein and non-protein nitrogen and sedimentation rate in chronic rheumatic disorders, Quart. Jr. Med., 1935, iv, 269-277. Google Scholar2. BING J: The formol-gel reaction and other globulin reactions, Acta med. Scand., 1937, xci, 336-356. Google Scholar3. DAVIS JS: Protein studies in atrophic (rheumatoid) and hypertrophic arthritis, Jr. Lab. and Clin. Med., 1936, xxi, 478-490. Google Scholar4. GIBSONKERSLEY HJGD: Gout, Med. Press and Circ., 1934, cxcvi, 5164. Google Scholar5. GIBSONRICHARDSON HJEW: The formol-gel test (aldehyde reaction) in chronic rheumatism, Acta Rheumatol., 1938, x, 30-33. Google Scholar6. SCULLBACHPEMBERTON CWTFR: The serum proteins in arthritis, ANN. INT. MED., 1939, xii, 1463-1472. Google Scholar7. WISEGUTMAN CRAB: The formol-gel reaction: a convenient preliminary test for hyperglobulinemia, Am. Jr. Med. Sci., 1937, cxciv, 263-270. CrossrefGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Philadelphia, Pennsylvania*Received for publication June 18, 1940.From the Abington Memorial Hospital, Abington, Pa.The expenses of this investigation were defrayed in part by a grant in memory of Alexander B. Coxe. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byThe Formol-Gel Test on Plasma and Serum in Rheumatic Cases: Correlation Studies and a Suggestion that Non-Rouleaux-Forming Pathological Globulins may be of Significance in Rheumatism 1 December 1940Volume 14, Issue 6Page: 993-1000KeywordsBloodBlood plasmaFibrinogenGlobulinsHyperglobulinemiaMemoryPlasma proteinsResearch laboratoriesSerum proteins ePublished: 1 December 2008 Issue Published: 1 December 1940 PDF downloadLoading ...