The Food Animal Residue Avoidance Databank (FARAD): a computer databank of the pharmacokinetics of drugs, pesticides and environmental chemicals in food animals

Abstract

The Food Animal Residue Avoidance Databank (FARAD) is a computer databank of information on chemicals considered to be actual or potential residue problems in the United States. FARAD has been developed under the auspices of the United States Department of Agriculture Extension Service, Residue Avoidance Program (RAP). FARAD includes a listing of all drugs approved by the Food and Drug Administration for use in food animals, all the tissue, egg and milk tolerances for 119 chemicals, and information on the chemical properties of these chemicals. The major focus of FARAD has been to collect all published information on the pharmacokinetics of these chemicals in food and non-food animal species. FARAD currently contains information on 938 proprietary drug preparations approved by FDA, 253 residue tolerances, and over 3000 pharmacokinetic entries linked to over 700 bibliographic citations. After completion of data extraction and entry into FARAD, this information will be used for making detailed analysis of interspecies differences in pharmacokinetics, to study disease-induced changes in pharmacokinetics, and to study the relationship of serum pharmacokinetics to tissue residues.