Abstract

The first total synthesis of veiutamine, a new type of pyrroroiminoquinone marine alkaloid bearing a p-hydroxybenzyl substituent at C-6, has been achieved. The key step of the synthesis is 6-selective functionalization of the 1,3,4,5-tetrahydropyrrolo[4,3,2- de]quinoline nucleus via N-Boc-directed lithiation.

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