Abstract
The occurrence for patients who have the co-existence of Parkinson’s Disease (PD) and Myasthenia Gravis (MG) is rare. This study attempted to investigate the feasibility of physical therapy on a patient with PD and MG. A 56-year-old male patient had MG for 42 years and PD for 10 years. He received physical therapy, including the 5-minute gait training and balance training, twice per week for 8 weeks. Quantitative Myasthenia Gravis Score (QMGs), Modified Barthel Index (MBI), Berg Balance Scale (BBS), and Parkinson’s Disease Questionnaire (PDQ-39) were used at baseline and post-intervention evaluation. The Unified Parkinson’s Disease Rating Scale (UPDRS) activities of daily living part (UPDRS-II) and motor part (UPDRS-III) were performed every two weeks until the end of intervention. After the intervention of 8 weeks, QMGs decreased by 3 (-43%), BBS increased by 4 (9%), MBI increased by 12 (14%), and PDQ-39 decreased by 5 (-11%). UPDRS-II, UPDRS-III and total UPDRS gradually decreased by 2 (-14%), 6 (-18%), and 8 (-17%) respectively during the intervention. With improved results of clinical scales, motor and ADL functions of this patient were enhanced. Our results suggested that physical therapy on the patient with PD and MG was feasible and effective, which deserves more attention and warrants further research. Keywords: Parkinson’s disease; Myasthenia gravis; physical therapy; UPDRS.
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