The factors limiting the diagnostic accuracy of myocardial perfusion cardiac magnetic resonance imaging: coronary flow reserve and amount of myocardial scar

Masaki Ishida,Motonori Nagata,Hajime Sakuma,Nanaka Ishida,Kakuya Kitagawa,Shiro Nakamori,Shingo Kato,Hiroshi Nakajima

doi:10.1186/1532-429x-14-s1-o88

Abstract

Background Perfusion cardiac magnetic resonance (CMR) imaging has emerged as an important clinical tool for the accurate detection of myocardial ischemia caused by significant coronary artery disease (CAD), whereas most previous studies demonstrated the diagnostic accuracy of perfusion CMR in a highly selected patient population such as those without previous myocardial infarction or lower ejection fraction (EF) etc. In the real clinical practice, however, we may encounter the patients with multiple factors affecting the accurate CMR myocardial perfusion assessment. The aim of this study was to identify the factors reducing the sensitivity of perfusion CMR for predicting significant CAD determined by the coronary angiography (CAG). Methods

Highlights

Perfusion cardiac magnetic resonance (CMR) imaging has emerged as an important clinical tool for the accurate detection of myocardial ischemia caused by significant coronary artery disease (CAD), whereas most previous studies demonstrated the diagnostic accuracy of perfusion CMR in a highly selected patient population such as those without previous myocardial infarction or lower ejection fraction (EF) etc
The aim of this study was to identify the factors reducing the sensitivity of perfusion CMR for predicting significant CAD determined by the coronary angiography (CAG)
Per-territory analysis demonstrated the sensitivity of perfusion CMR for predicting significant CAD was 77.1% whilst overall perpatient analysis indicated a sensitivity of 85.5%

Summary

Introduction

Perfusion cardiac magnetic resonance (CMR) imaging has emerged as an important clinical tool for the accurate detection of myocardial ischemia caused by significant coronary artery disease (CAD), whereas most previous studies demonstrated the diagnostic accuracy of perfusion CMR in a highly selected patient population such as those without previous myocardial infarction or lower ejection fraction (EF) etc. In the real clinical practice, we may encounter the patients with multiple factors affecting the accurate CMR myocardial perfusion assessment. The aim of this study was to identify the factors reducing the sensitivity of perfusion CMR for predicting significant CAD determined by the coronary angiography (CAG)

Objectives

Methods

Results