Abstract

Objective To valuation the effect of varicella vaccine's emergent vaccination and to understand the sero prevalence of varicella-zoster virus (VZV).Methods Sevevteen schools which had Chickenpox outbreak in the years of 2004～2006 were chosen as the field of epidemiological study.The chickenpox patients and close contects in 5 schools of them were investigated in Questionnaire.And we collected 85 serum samples of students before and after immunity in 2 schools to test IgG antibody of VZV using ELISA.Results The attack rates of chickenpox in the schools before and after emergent vaccination are 6.22％ and 1.65％.The difference was significant(x2=10.99,P＜0.01).The attack rate of exposure group was significant lower than the control group(x2=20.70,P＜0.01).Antibodies effective rate after immunity was 90.70％,Antibody positive rate was 87.80％,and Immune success rate was 70.70％.Condusion Emergent vaccination can effectively control the chickenpox outbreak.So the result of study suggests that emergent vaccination should be done immediately once a chickenpox case has occured in a school. Key words: varicella; vaccine emergent vaccination; Vaccine efficacy

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