The enhancement features of hepatocelluar carcinoma using 320-row CT multi-phase dynamic volumetric contrast scan

Abstract

Objective To investigate the diagnostic value of 320-row CT multi-phase dynamic volumetric contrast scan for hepatocellular carcinoma (HCC).Methods 40 HCC patients were investigated using a 320-row CT multi-phase dynamic volumetric contrast scan (Aquilion One; Toshiba Medical,Otawara,Japan).The time density curves (TDC) of hepatic artery,hepatocelluar carcinoma and liver parenchyma could be delineated on the basis of the initial data.The time to peak enhancement and the total time of duration enhancement of the 40 HCCs were recorded.The enhancement of tumor in the whole arterial phase was analyzed.Results 40 HCCs were detected by the 320-row CT multiphase dynamic volumetric contrast scan.The mean time to peak enhancement of 40 HCCs was 29(22-36)s.The mean time of durative enhancement was 14s.31 hepatic perfusion disorders (HPD) were detected by the 320-row CT multi-phase dynamic volumetric contrast scan,showing dot,patchy,strip and wedge.The mean time to enhancement was 22 s.The mean time of durative enhancement was 12s.The mean time of restoring to isodensity was 34s.Conclusions 320-row CT multi-phase dynamic volumetric contrast scan with a low dose of contrast agent could result in real-time capture of accurate information for the time to peak enhancement and the total time of duration enhancement of tumor,thus overally reflected the feature and mechanism of tumor enhancement,and provided important image information for diagnosis and differential diagnosis of HCC. Key words: Hepatocelluar carcinoma; Dynamic contrast scan, multi-phase