Abstract
Background: Sickle Cell Disease (SCD) is a chronic and debilitating disease that can affect almost any organ system in the body; hence, it is associated with a broad range of complications and comorbidities that may have a profound impact on a patients’ quality of life through medical and mental health consequences. Psychosocial and affective comorbidities are prevalent in SCD and could considerably influence disease outcomes; however, treatment options for SCD psychosocial sequelae are suboptimal, and evidence on their effectiveness is limited. Case Report: We report a 21-year-old African American female with a history of SCD and recurrent hospital admissions due to acute SCD complications, who was referred to the consultation-liaison psychiatry service for evaluation of psychiatric comorbidities and management recommendations. Conclusion: This case demonstrates the complexity of the relationship between somatic complications and neuropsychiatric disorders in SCD and highlights the importance of early identification and management of mental health conditions in this patient population. We emphasize treatment challenges and the need for large scale research on pharmacotherapies and nonpharmacological interventions in treating psychosocial comorbidities associated with SCD.
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