Abstract

We are in the process of recovering patients undergoing treatments with Sophora flavescens (experimental) or potassium permanganate (control) fumigation following anal fistula surgery. The experimental group had a shorter wound healing time and lower pain measurement on the Visual Analogue Scale on postoperative days 7 and 14 than the control group (P < 0.05). Although no inter-group notable difference was identified in clinical efficacy (P > 0.05), the anal function of the experimental group was improved, and the levels of pro-inflammatory cytokines were lower after treatment (P < 0.05). Assessment of the nutritional status after surgery, key to postoperative recovery, showed that the weight and upper arm circumference decreased in both groups after treatment, but the experimental group was higher than the control group (P < 0.05), and prealbumin, albumin, and transferrin were also higher in the experimental group than in the control group after treatment (P < 0.05). Finally, the two groups did not differ significantly in adverse reactions and relapse (P > 0.05). SF facilitates wound healing after anal fistula surgery, mitigates patient pain, and improves anal health.

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