Abstract

Background In recent years, the incidence of endometrial cancer (EC) has been on the rise worldwide. The purpose of this study was to investigate the efficacy of psychological care and Chinese herbal decoction in EC patients with postoperative chemotherapy. Methods 80 EC patients with postoperative chemotherapy were randomly divided into the observation group and control group. The control group was given psychotherapy. The observation group was given psychological care plus Chinese herbal decoction treatment. HE4, CA125, traditional Chinese medicine (TCM) syndrome scores, toxic and side effects, and quality of life scores before and after treatment were observed. Results After treatment, the total effective rate of the observation group was higher than that of the control group. After treatment, serum HE4 and CA125 levels in the observation group were lower than those in the control group. In addition, CD3+ and CD4+ levels in the observation group were higher than those in the control group. Meanwhile, the CD8+ level in the observation group was lower than that in the control group. Compared with the control group, the quality of life in the observation group was significantly improved, and the incidence of adverse reactions was reduced. Conclusion Chinese herbal decoction combined with psychological care can improve the clinical symptoms, alleviate the toxic and side effects, and improve the life quality of EC patients with postoperative chemotherapy.

Highlights

  • Endometrial carcinoma (EC) is one of three common malignancies in the female reproductive system. e incidence of postmenopausal women in Western developed countries is higher, and the incidence of EC in developing countries is second only to cervical cancer [1, 2]

  • Chinese herbal decoction combined with psychological care can improve the clinical symptoms, alleviate the toxic and side effects, and improve the life quality of EC patients with postoperative chemotherapy

  • In order to seek effective methods to consolidate the effect of chemotherapy and adjuvant therapy to relieve discomfort, reduce functional damage, and improve the life quality, this study investigated the efficacy of psychological care and Chinese herbal decoction in EC patients with postoperative chemotherapy

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Summary

Introduction

Endometrial carcinoma (EC) is one of three common malignancies in the female reproductive system. e incidence of postmenopausal women in Western developed countries is higher, and the incidence of EC in developing countries is second only to cervical cancer [1, 2]. E purpose of this study was to investigate the efficacy of psychological care and Chinese herbal decoction in EC patients with postoperative chemotherapy. 80 EC patients with postoperative chemotherapy were randomly divided into the observation group and control group. E observation group was given psychological care plus Chinese herbal decoction treatment. The total effective rate of the observation group was higher than that of the control group. Serum HE4 and CA125 levels in the observation group were lower than those in the control group. Compared with the control group, the quality of life in the observation group was significantly improved, and the incidence of adverse reactions was reduced. Chinese herbal decoction combined with psychological care can improve the clinical symptoms, alleviate the toxic and side effects, and improve the life quality of EC patients with postoperative chemotherapy

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